Experimental and Monte Carlo dosimetric characterization of a 1 cm (103)Pd brachytherapy source.
نویسندگان
چکیده
PURPOSE To determine the in-air azimuthal anisotropy and in-water dose distribution for the 1 cm length of a new elongated (103)Pd brachytherapy source through both experimental measurements and Monte Carlo (MC) simulations. Measured and MC-calculated dose distributions were used to determine the American Association of Physicists in Medicine Task Group No. 43 (TG-43) dosimetry parameters for this source. METHODS AND MATERIALS The in-air azimuthal anisotropy of the source was measured with a NaI scintillation detector and was simulated with the MCNP5 radiation transport code. Measured and MC results were normalized to their respective mean values and then compared. The source dose distribution was determined from measurements with LiF:Mg,Ti thermoluminescent dosimeter (TLD) microcubes and MC simulations. TG-43 dosimetry parameters for the source, including the dose-rate constant, Λ, two-dimensional anisotropy function, F(r, θ), and line-source radial dose function, gL(r), were determined from the TLD measurements and MC simulations. RESULTS NaI scintillation detector measurements and MC simulations of the in-air azimuthal anisotropy of the source showed that ≥95% of the normalized values for each source were within 1.2% of the mean value. TLD measurements and MC simulations of Λ, F(r, θ), and gL(r) agreed to within the associated uncertainties. CONCLUSIONS This new (103)Pd source exhibits a high level of azimuthal symmetry as indicated by the measured and MC-calculated results for the in-air azimuthal anisotropy. TG-43 dosimetry parameters for the source were determined through TLD measurements and MC simulations.
منابع مشابه
Dosimetric characterization of a high dose rate 192I source for brachytherapy application using Monte Carlo simulation and benchmarking with thermoluminescent dosimetry
Background: The purpose of this project was to derive the brachytherapy dosimetric functions described by American Association of Physicists in Medicine (AAPM) TG-43 U1 based on high dose rate 192I sources. Materials and Methods: The method utilized included both simulation of the designed Polymethyl methacrylate (PMMA) phantom using the Monte Carlo of MCNP4C and benchmarking of the simulation ...
متن کاملComparison of dosimetry parameters of two commercially available Iodine brachytherapy seeds using Monte Carlo calculations
Background: Iodine brachytherapy sources with low photon energies have been widely used in treating cancerous tumors. Dosimetric parameters of brachytherapy sources should be determined according to AAPM TG-43U1 recommendations before clinical use. Monte Carlo codes are reliable tools in calculation of these parameters for brachytherapy sources. Materials and Methods: Dosimetric param...
متن کاملSU-E-T-319: Monte Carlo Characterization of a New Directional Pd-103 High Dose Rate Source for Brachytherapy Application.
PURPOSE Standard brachytherapy sources emit radiation in a non-preferential direction away from the source. Though treatment outcomes are good, this can lead to late skin and subcutaneous toxicities in sensitive structures. Proposed low dose rate directional sources for interstitial brachytherapy, showed to have an improvement in the dose uniformity within the subcutaneous volume, reduction in ...
متن کاملDetermination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources
Objective: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study is to obtain TG-43 dosimetric parameters for 60Co, 137Cs, 192Ir and 103Pd brachyt...
متن کاملDetermination of Dosimetric Parameters of the Second Model of Pd-103 Seed Manufactured at Agricultural, Medical and Industrial Research School
Introduction: The use of low energy isotopes such as 103 Pd in brachytherapy for the treatment of cancers such as prostate, eye, head, neck, breast and cervix is increasing. In this regard, different models of Pd- 103 seeds have been designed and manufactured at the Agricultural, Medical and Industrial Research School (AMIRS) of Atomic Energy Organization of Iran. In this resear...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Brachytherapy
دوره 13 6 شماره
صفحات -
تاریخ انتشار 2014